Jennifer Aniston, Demi Moore and Alicia Keys are the beautiful ladies of Glamour’s October issue!

In the issue out September 6, the three talk about the deadly disease that brought them together—breast cancer. All three actresses directed a series of short films for Lifetime entitled Five, showing how breast cancer affects not only women and their bodies, but also their friendships and families. Of course, dishing about their personal lives in between!

Aniston, an executive producer of Five, directed Mia, a film about a woman who thinks that her initial diagnosis is now a death sentence.

“We were intrigued by the challenge of creating short stories that would defy audiences’ expectation of the subject. We wanted to balance the drama with humor and irreverence because that’s what’s helped our friends who’ve faced this get through their treatment. We wanted stories that were informative without being heavy-handed. Oh, and they needed to be brilliantly written. Other than that, our goals were small.”

Other then Jen being just flat out fabulous, her love life is always the center of attention for every tabloid magazine, these days with Justin Theroux.

“I would say I couldn’t be in a relationship without equality, generosity, integrity, spirit, kindness and humor. And awesomeness.”

Moore directed Charlotte, about a little girl who watches her mother die of breast cancer and becomes determined to help others fight the disease.

“I think that so often there is that ‘out of sight, out of mind’ feeling, like breast cancer is happening to other people, not you. Before this project came up. Even I really didn’t want to pay attention. I feel that this came to me to make me pay attention.”

The actress, who just gets more gorgeous with age, isn’t shy about sharing her life with the world via Twitter and loves expressing herself any way possible.

“I saw Twitter as this opportunity to connect with people and actually show a side of myself that is much lighter. And all of a sudden people were getting to know me, and I was connecting with people. At its core, Twitter is about sharing, and I think that in life we never feel better or more energized than when we’re giving to someone else.”

Keys directed Lili, a film about a 35-year-old whose breast cancer forces her to work on her relationship with her mother.

“After I read the scripts, I felt like this was something important, and I wanted to be a part of it. I chose Lili because she’s close to my age and I understood the family dynamic. I had an immediate idea of what I could bring to it.”

This songstress was even inspired after visiting Egypt to name her son after the eye opening experience.

To check out the full interview, head on over to Glamour via this link.